Politecnico di Milano

Grants & Projects

Funded research projects driving innovation in organ-on-chip technology and microfluidic systems.

Current Projects

AI-RITMIA

AI-assisted peRsonalized heart-on-chIp as advanced diagnostic Tool for clinical significance assessMent of Inherited cArdiomyopathies

2026-2029
EuropeanHORIZON-EIC-2025-PATHFINDEROPENRole: Coordinator

PHOENIX

Precision Human Organs-on-chip for Enhanced Neuro-muscular and Cardiac Studies

2025-2028
EuropeanHORIZON-HLTH-2024-TOOL-05-06-two-stageRole: Coordinator

MATRIx

Understanding Nanoparticle Transport Mechanisms in the Melanoma Microenvironment via a Tumor-on-a-Chip Approach

2025-2028
EuropeanHORIZON-MSCA-2024-PF-01-01Role: Coordinator

BuonMarrow

Bone Marrow-on-Chip as smart sensor of lung cancer relapse

2024-2027
EuropeanEIC-Pathfinder-Open-2023Role: Coordinator

EvOoC

Evolving Organs-on-Chip from developmental engineering to "mechanical re-evolution"

2023-2029
EuropeanERC-2022-StGRole: Coordinator

Past Projects

vEIColo: AI-RITMIA

ID 121267

2025Call year: 2024
ItalianFondazione Compagnia di San PaoloRole: Coordinator

AI-HEART

P20229Z3CM

2023-2026Call year: 2022
ItalianPRIN-MUR-PNRRRole: Coordinator

RECOVERY

P2022S94EZ

2023-2026Call year: 2022
ItalianPRIN-MUR-PNRRRole: Coordinator

DESIRE

2022YS87H7

2023-2026Call year: 2022
ItalianPRIN-MURRole: Partner

Endothelial von Willebrand factor and the tissue-specific regulation of angiogenesis and vascular integrity

ID 6261996

2024-2026Call year: 2022
UK-MRCMRCRole: Partner

Exploring the role of MLIP in LMNA-Cardiomyopathy in iPSC-based human cardiac models

GJC22040

2023-2026Call year: 2022
ItalianFondazione Cariplo + Fondazione TelethonRole: Partner

Unravelling the molecular correlation between mechanical injuries and cartilage hypertrophy in osteoarthritis in a synovial joint-on-chip model

2021-1564

2022-2026Call year: 2021
ItalianFondazione CariploRole: Coordinator

SINERGIA - advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

GA-860715

2019-2024Call year: 2018
EuropeanH2020-MSCA-ITN-2019Role: Coordinator

uKNEEversal: a miniaturized 3D in vitro model of human joint to gain new knowledge on Osteoarthritis pathophysiology

GA-841975

2019-2022Call year: 2018
EuropeanH2020-MSCA-IF-2018Role: Coordinator

BrainCircuit-on-chip

GA-842423

2019Call year: 2018
EuropeanERC-2018-PoCRole: Partner

uKNEEque: a 3D microfluidic osteochondral model to investigate mechanisms triggering age-related joint pathologies and therapeutic effects of bioactive factors produced by nasal chondrocytes

2018-0551

2019-2022Call year: 2018
ItalianFondazione CariploRole: Coordinator

A 3D microfluidic osteochondral model to investigate mechanisms triggering osteoarthritis and therapeutic effects of bioactive factors produced by human nasal chondrocytes

310030_175660

2018-2021Call year: 2017
SwissSNFRole: Partner

Cholangiocytes-on-a-chip: a platform to identify medical therapy

GR-2016-02364990

2018-2019Call year: 2016
ItalianMin SaluteRole: Partner

Creation of a national network of IIZZSS laboratories involved in the development and application of alternative methods, and in the implementation of the good laboratory practice system

2017-2018Call year: 2016
ItalianMin SaluteRole: Partner

Development of methodologies alternative to the animal use in the activities of diagnostics and control of biological products in Zooprophylactic Institutes

2016-2017Call year: 2015
ItalianMin SaluteRole: Partner

Microfluidic organotypic model of monocyte transendothelial migration to the joint for the screening of promising therapeutic strategies in obese osteoarthritic patients

PE-2013-02356613

2016-2018Call year: 2014
ItalianMin SaluteRole: Partner

Nanoparticles transport through the blood brain barrier in health and disease

2013-1048

2014-2017Call year: 2013
ItalianFondazione CariploRole: Partner

Smart nanostructured hydrogel systems for generation of contractile cardiac organoids

2012-0891

2013-2016Call year: 2012
ItalianFondazione CariploRole: Coordinator

SELECTIVE CEREBROSPINAL FLUID HYPOTHERMIA: BIOENGINEERING DEVELOPMENT AND IN VIVO STUDY OF AN INTRAVENTRICULAR COOLING DEVICE (V-COOL) FOR ACUTE STROKE THERAPY

162/GR-2011-02347879

2013-2016Call year: 2011
ItalianMin SaluteRole: Partner

Lab on Chip for testing Myelotoxicity effect of Drugs and chemicals

2011-0322

2012-2015Call year: 2011
ItalianFondazione CariploRole: Coordinator

Microfluidic large scale integrated devices with individual chamber control functionalized

2008-2531

2009-2012Call year: 2008
ItalianFondazione CariploRole: Coordinator