MiMic
Innovation Lab
Advancing microfluidic technologies and organ-on-chip systems for the future of biomedical research at Politecnico di Milano
About Our Lab
The MiMic Lab at the Department of Electronics, Information and Bioengineering (DEIB) of Politecnico di Milano focuses on developing cutting-edge microfluidic technologies and organ-on-chip systems.
Our interdisciplinary team combines expertise in bioengineering, microfabrication, and cell biology to create innovative platforms for drug discovery, disease modeling, and personalized medicine.
Meet Our Team
EUROoCS Annual Meeting 2024, Politecnico di Milano
Lab Highlights
A curated selection of peer-reviewed results, core platforms, and leadership roles.
Featured Publications
Selected peer-reviewed papers showcasing key lab contributions.
- VWF deficiency impairs angiogenesis via Angpt-2Blood (2026)
- Compartmentalized Joint-on-Chip modelAdvanced Science (2025)
- Gut-on-a-chip with human faecal samples + peristalsisNature Biomedical Engineering (2025)
Core Capabilities
From microfluidic platforms to human-relevant models and technology transfer.
- Microfabrication & soft lithographyRapid iteration of microfluidic chips
- Human-relevant biological modelsDisease-focused models built on patient-derived / human systems
- IP & technology transfer7 patents filed, 3 transferred (licensing/translation)
Leadership & Awards
Leadership roles and translational impact across the European OoC/MPS ecosystem.
- Marco RasponiChair, EUROoCS
- Paola OcchettaVice President (Regulatory Adoption & Partnerships), IAMPS
- BiomimXPolitecnico di Milano spin-off (2017) — organs-on-chip platforms
Research Topics
Explore our main research focus areas and ongoing projects
Latest News
Stay updated with our latest achievements and upcoming events
PHOENIX Consortium at THE 3R LÄND Conference in Tübingen
Members of the PHOENIX consortium gathered at THE 3R LÄND Conference, held March 24–26, 2026, at the University of Tübingen, Germany. Organized by the 3R-Center Tübingen and Prof. Peter Loskill, the conference brought together leading experts to discuss the latest advances in organoids, organ-on-chip, and in silico models for reducing animal testing. Marco Rasponi delivered the opening talk of the "Innovation in Organ-on-Chip" session, and Victoria Rabsiun Aramburu (BiomimX) presented on human 3D cardiac organ-on-chip as advanced preclinical models. PHOENIX partners NMI, MCS, and BiomimX presented a poster showcasing the first results of the project on next-generation cardiac and neuro-muscular organs-on-chip. Our PI Paola Occhetta also presented a poster that sparked inspiring exchanges of ideas and insights, while PhD student Giacomo Cretti presented on vascularized tumor-vessel crosstalk on-chip, with results obtained within the MUSA project (PNRR). The event was a valuable opportunity for the consortium partners to meet and strengthen their collaboration.
EUROoCS 2026 — Call for Abstracts Open
Under the chairmanship of Prof. Marco Rasponi, the European Organ-on-Chip Society (EUROoCS) has opened abstract submissions for its 2026 Annual Meeting, to be held in Braga, Portugal (June 22–24, 2026). The conference will bring together the international MPS community for three days of cutting-edge science, with over 200 abstracts already received. Submit your work and join us in Braga!
Paola Occhetta Appointed Vice President of IAMPS
Prof. Paola Occhetta has been appointed Vice President for Regulatory Adoption & Partnerships of IAMPS — the Industry Alliance for MicroPhysiological Systems, the world's first industry association dedicated to representing MPS providers across Europe. In this role, she will support standardisation, validation, and constructive dialogue with regulators, accelerating the acceptance of MPS technologies and strengthening Europe's position as a global leader in human-relevant in vitro models.
Get in Touch
Interested in learning more about what we do, collaborating with us, or joining our team?
Contact Us